This is what I thought about when I woke up this morning. Aesthetic significance, as well as aspects of form, scale, fabric, setting etc, also covers the EXPERIENCE of being in a place - visual, acoustic, olfactory, the touch and taste.
In space, you would always be inside a spacecraft or inside a spacesuit. You take your environment with you, so touch, smell, sound, taste are unrelated to the outside. They remain more or less the same wherever you are. The only sense that could be drawn into apprehension of a spacecraft is sight. So the aesthetic significance of material culture in space is all about how things look.
Of course human sight takes in only a narrow portion of the wavelength, and spacecraft, one would imagine, may appear very differently in UV, IR, radio, etc etc, just like everything else in the universe.